MCI cohort

Group 1

Group 2

Group 3

p value (ANOVA)

Number of subjects (f/m)

79 (42/37)

27 (14/13)

27 (15/12)

25 (13/12)

Age (years)

69.2 ± 2.3

66.8 ± 6.8

69.4 ± 8.7

71.5 ± 6.9

0.1

Education (years)

7.7 ± 0.8

8.3 ± 4.5

6.7 ± 3.1

8.2 ± 4.6

0.2

MMSE

27.1 ± 0.4

27.5 ± 1.5

27.4 ± 1.5

26.6 ± 1.8

0.1

Total AHC volume

6965.3 ± 1248.8

8151.2 ± 436.4

7082.7 ± 266.9

5661.8 ± 720.4

0.00001

AHC-hippocampal volume (mm³)

4891.7 ± 902.6

5771.6 ± 361.1

4935.6 ± 380.9

3967.9 ± 650.3

0.00001

AHC-amygdalar volume (mm³)

2073.5 ± 348.7

2379.6 ± 321.3

2147.1 ± 301.3

1693.9 ± 288.5

0.0001

individual hippocampal volume (mm³)

4889.8 ± 962.4

5809.6 ± 314.2

4969.4 ± 257.6

3890.1 ± 551.4

0.00001

individual amygdalar volume (mm³)

2071.7 ± 446.4

2514.4 ± 259.5

2079.2 ± 122.8

1621.6 ± 185.2

0.0001

White matter hyperintensities (mm³)

3.8 ± 0.5

3.2 ± 2.8

4.2 ± 3.8

4.1 ± 3.6

0.7